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        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of retinoblastoma (RB)
ncRNA name BANCR
ncRNA Category lncRNA
ID 100885775
Ensembl ENSG00000278910
Synonyms LINC00586
Disease name retinoblastoma (RB)
Species Homo sapiens
Tissues/Cell_line RB samples and normal retinas; RB cell lines WERI-RB1 and Y79
Methods qPCR, siRNA transfection, MTT assay, colony formation assay, transwell assay
Expression pattern up-regulated
Functional description LncRNA BANCR is overexpressed in retinoblastoma tissues and cell lines and is associated with tumor size, choroidal invasion, and optic nerve invasion. Moreover, patients with high levels of lncRNA BANCR expression had poorer survival than those with lower levels of lncRNA BANCR expression.
PubMed ID 25894373
Year 2015
Title Long non-coding RNA BANCR regulates growth and metastasis and is associated with poor prognosis in retinoblastoma.
Drug-related ncRNA NO

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